The FDA is conducting a workshop to discuss the science (lack thereof, really) of Morphine Milligram Equivalents as it applies to the atrocious CDC 2016 Opioid Prescribing Guidelines. Public comments ...

All opioid equivalencies should be considered approximations only and can be affected by interpatient variability, type of pain (eg, acute vs. chronic), chronic administration, tolerance, etc.

In a letter to the FDA, the American Society of Anesthesiologists has addressed public health concerns associated with the use of equianalgesic opioid conversion tables and has recommended a staged ...

A patient who has been taking an opioid for an extended period of time may develop a degree of tolerance to it; however, when converting to another opioid, only a part of this tolerance may carry over ...